Pharma Tech Outlook: Pharma Tech Magazine

LucasPye BIO: Enabling Next-Gen Drug and Biologics Development

Top 10 CMOs - 2020

The global contract manufacturing market is growing at an unprecedented rate today. The factors driving this growth are the prevalence of chronic diseases and the demand for medicines, which are pushing the pharmaceutical companies to increase the production of existing and new drugs. Mainly due to the ongoing COVID-19 outbreak, pharmaceuticals are investing heavily in research and development to find a cure for the highly contagious viral disease. Other factors contributing to the rise of contract manufacturing organizations are the pharmaceutical companies needing to free up in-house resources for different projects and improve flexibility in terms of the supply chain, timelines, and regulatory management.

The companies in the pharmaceutical contract development and manufacturing market are following the trend of mergers and acquisitions and forming new alliances to expand their capabilities and global market reach. This strategy is helping them increase their production while maintaining costs and getting access to the latest technology and services. And as a result of industry consolidations, there are changes being noticed in key personnel, relationships, policy, and even company objectives. These changes are further pushing pharmaceutical companies to review their past sourcing decisions. Besides, different geographic regions and countries are mandating the use of local CMOs to eliminate supply chain bottlenecks due to COVID-19 lockdown.

At this juncture, a wide variety of contract manufacturing organizations are entering the industry with a set of advanced and integrated offerings. Pharma Tech Outlook has compiled a list of the top 10 CMOs to help pharmaceutical companies improve outcomes and simultaneously enable growth in the industry. The list comprises of prominent organizations in the industry that will enhance pharma manufacturing practices in compliance with stringent regulations. Besides, the magazine also includes insights from thought leaders in the sector on the industry trends, best practices, recent innovations, and their advice for the aspiring CXOs.

We present to you Pharma Tech Outlook’s, “Top 10 CMOs – 2020.”

TOP VENDORS

Top CMOs

Batavia Biosciences

Batavia Biosciences significantly contributes to ease human suffering from infectious diseases and cancer by improving the success rate in the translation of candidate medicines from discovery to the clinic. They offer innovative technologies and in-depth know-how in order to help their partners to complete preclinical phases in biopharmaceutical product development at higher speed, reduced costs and increased success. The company focuses on the early stages of product development including cell line generation, upstream process development, purification development, product characterization and clinical manufacturing. Headquartered in Leiden, the Netherlands, with a subsidiary in Woburn, Massachusetts, and offices in Hong Kong, Batavia Biosciences is privileged to have strong strategic partners worldwide

www.bataviabiosciences.com
BirdoTech

A CRO that specializes in the R&D of pharmaceutical raw materials and active pharmaceutical intermediates. BirdoTech offers full-time equivalent (FTE) medicinal chemistry services supporting early drug discovery research. With their in-house process chemistry team, synthetic routes are optimized to address raw material costs, environmental safety, and overall reliability for supply resilience. BirdoTech can tailor process development strategies, regardless of whether a project is in the preclinical stage or is ready for commercialization

www.birdotech.com
IDT Biologika

A global biopharmaceutical contract development and manufacturing organization (CDMO) specializing in the production of innovative live viral vaccines, viral vectors for gene and immune therapeutics as well as fill/finish of sterile liquid and lyophilized biologics to improve human health worldwide. The company offers clients in B2B business a single source CDMO partner at our sites in Germany and the USA, with seamless end-to-end solutions and the ability to nimbly scale projects from development through to commercialization. This includes process development, drug substance manufacture, drug product manufacture, packaging, quality control/analytics and storage

idt-biologika.com
LucasPye BIO

Pennsylvania-based LucasPye BIO offers bio-manufacturing services that financially support new biologics discovered by life science entrepreneurs, biopharmaceutical firms, and non-profit organizations bio-manufacturing services. The company is set to become the first CDMO to utilize MasterControl, an e-documentation platform which enables the real-time tracking of all drug development project-related tasks. With its e-documention platform, LucasPye BIO ensures that all the proprietary information is shared securely via MasterControl’s e-documentation platform’s protected network, preventing loss and potential abuse of sensitive data. At the same time, with the first-of-its-kind Commercial Life Science Co-Working/Wet Lab Facility—named HelaPlex, LucasPye BIO thrives on bringing innovation into everything that they do. To this end, the company has garnered access to superior mammalian, gene vector, viral vector, and bacterial cell line technologies that enhance drug development processes for clients

www.lucaspyebio.com
PureNSM

PureNSM is at the forefront of manufacturing clean and tested dietary supplements. They specialize in manufacturing excipient-free capsules and tablets without magnesium stearate and preservative-free liquids supplements. Since our inception in 1993, our aim has always been to manufacture and deliver products that are pure, safe, and potent, without toxic flow agents, fillers, artificial colors, or binders. PureNSM newest product offering is oil filled capsules, not to be confused by softgels that includes a lot of plasticizers. The oil in capsules use the normal Tapioca, Gel, or HPMC capsules you have become accustomed to

purensm.com
Ajinomoto Bio-Pharma Services

Ajinomoto Bio-Pharma Services is a fully integrated contract development and manufacturing organization with sites in Belgium, United States, Japan, and India providing comprehensive development, cGMP manufacturing, and aseptic fill finish services for small and large molecule APIs and intermediates. Ajinomoto Bio-Pharma Services offers a broad range of innovative platforms and capabilities for pre-clinical and pilot programs to commercial quantities, including: Corynex® protein expression technology, oligonucleotide synthesis, antibody drug conjugations (ADC), high potency APIs (HPAPI), biocatalysis, continuous flow manufacturing and more. Ajinomoto Bio-Pharma Services is dedicated to providing a high level of quality and service to meet our client’s needs
Boehringer Ingelheim

At Boehringer Ingelheim we create value through innovation with one clear goal: to improve the lives of patients. We develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company, we focus on long-term performance. We are powered by 50.000 employees globally who nurture a diverse, collaborative and inclusive culture. Learning and development for all employees is key, because your growth is our growth
Contract Pharmacal Corp

Contract Pharmacal Corp. (CPC) develops, manufactures and packages solid dose drugs and dietary supplements. CPC employs more than a thousand highly skilled professionals in its Hauppauge, NY facilities totaling 500,000 square feet and to date has commercialized over 5,000 products. The company develops approximately 100 new products per year, and has capacity to support manufacturing 15 billion tablets and capsules annually. CPC's customers rank among the world's top pharmaceutical companies, retailers and wholesalers. More than 60 customers around the globe rely on CPC from the early stages of product innovation and development to commercial manufacturing and packaging
Flexan

Flexan, LLC is a global manufactuer of custom, high-precision silicone, rubber, and thermoplastic components for a broad array of product and industry applications, primarily used in medical devices but including hearing technology, miniature pneumatics, industrial controls, and aerospace and defense industries, among others. Flexan, LLC markets it’s products under the FMI, Flexan, Medron, and IntroMed brands. The FMI, Medron, and IntroMed healthcare brands deliver cleanroom manufactured, assembled, and packaged silicone, and thermoplastic molded components for use in implantable Class III and disposable Class II and Class I medical devices. The Flexan brand is synomous with custom molding and expertise with molding difficult geometries as well as with bonding rubber to metal and other substrates, delivering high-precision, niche parts to a range of industries
Jubilant HollisterStier

Jubilant HollisterStier is an integrated contract manufacturer of sterile injectables, ophthalmics, otics and sterile and non-sterile topicals and liquids. Our facilities in North America provide specialized manufacturing for the pharmaceutical and biopharmaceutica industries. We provide a full-range of support and services to streamline the manufacturing process such as on-site assistance from process qualifications through product release